TFB2M Antikörper (N-Term)

Produktnummer ABIN2775816

Der Kaninchen Polyklonal anti-TFB2M Antikörper wird verwendet zum Nachweis von TFB2M in Proben von Human, Ratte, Pferd und Kaninchen. Er wurde validiert für WB und IHC.

Kurzübersicht für TFB2M Antikörper (N-Term) (ABIN2775816)

Target: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Reaktivität: Human, Ratte, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFB2M Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TFB2M Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: TFB2M Antibody - N-terminal region

Sequenz: ECNPGPGILT QALLEAGAKV VALESDKTFI PHLESLGKNL DGKLRVIHCD

Homologie: Horse: 100%, Human: 100%, Rabbit: 83%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against TFB2M. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TFB2M

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34471-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TFB2M

Target: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Andere Bezeichnung: TFB2M

Hintergrund:

Background Information: TFB2M is a S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. It is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. It stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.

Gene Name: Transcription factor B2, mitochondrial

Alternative Symbols: Hkp1, mtTFB2

Protein Name: Dimethyladenosine transferase 2, mitochondrial

Molekulargewicht: 45kDa

Gen-ID: 64216

NCBI Accession: NP_071761

UniProt: Q9H5Q4