HVCN1 Antikörper (C-Term)

Produktnummer ABIN783681

Produktdetails anti-HVCN1 Antikörper

Target: HVCN1 (Hydrogen Voltage-Gated Channel 1 (HVCN1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HVCN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antoibody detects HVCN1 / VSOP at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the carboxy terminus of human HVCN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu HVCN1

Target: HVCN1 (Hydrogen Voltage-Gated Channel 1 (HVCN1))

Andere Bezeichnung: HVCN1 / VSOP (HVCN1 Produkte)

Synonyme: zgc:92181 antikoerper, HVCN1 antikoerper, VSOP antikoerper, vsx1 antikoerper, HV1 antikoerper, 0610039P13Rik antikoerper, AI450555 antikoerper, BTS antikoerper, Vsop antikoerper, mVSOP antikoerper, RGD1310788 antikoerper, hydrogen voltage-gated channel 1 antikoerper, hydrogen voltage gated channel 1 pseudogene antikoerper, hydrogen voltage gated channel 1 antikoerper, voltage-gated hydrogen channel 1 antikoerper, hydrogen voltage gated channel 1 L homeolog antikoerper, hvcn1 antikoerper, LOC452241 antikoerper, HVCN1 antikoerper, Hvcn1 antikoerper, hvcn1.L antikoerper

Hintergrund: HVCN1 (hydrogen voltage-gated channel 1), a voltage gated proton channel protein that is highly expressed in immune tissues, mediates the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 may represent a new therapeutic target for B cell malignancies on continued signaling via the B cell antigen receptor.Synonyms: HV1, Hydrogen voltage-gated channel 1, Voltage sensor domain-only protein, Voltage-gated hydrogen channel 1

Gen-ID: 84329

NCBI Accession: NP_001035196

UniProt: Q96D96

Pathways: Proton Transport