HVCN1 Antikörper (C-Term)

Produktnummer ABIN6991389

Produktdetails anti-HVCN1 Antikörper

Target: HVCN1 (Hydrogen Voltage-Gated Channel 1 (HVCN1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HVCN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Aufreinigung: HVCN1 Antibody is affinity chromatography purified via peptide column.

Immunogen: HVCN1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human HVCN1. The immunogen is located within the last 50 amino acids of HVCN1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: HVCN1 antibody can be used for detection of HVCN1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: HVCN1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: HVCN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu HVCN1

Target: HVCN1 (Hydrogen Voltage-Gated Channel 1 (HVCN1))

Andere Bezeichnung: HVCN1 (HVCN1 Produkte)

Synonyme: zgc:92181 antikoerper, HVCN1 antikoerper, VSOP antikoerper, vsx1 antikoerper, HV1 antikoerper, 0610039P13Rik antikoerper, AI450555 antikoerper, BTS antikoerper, Vsop antikoerper, mVSOP antikoerper, RGD1310788 antikoerper, hydrogen voltage-gated channel 1 antikoerper, hydrogen voltage gated channel 1 pseudogene antikoerper, hydrogen voltage gated channel 1 antikoerper, voltage-gated hydrogen channel 1 antikoerper, hydrogen voltage gated channel 1 L homeolog antikoerper, hvcn1 antikoerper, LOC452241 antikoerper, HVCN1 antikoerper, Hvcn1 antikoerper, hvcn1.L antikoerper

Hintergrund: HVCN1 Antibody: HVCN1 (hydrogen voltage-gated channel 1), a voltage gated proton channel protein that is highly expressed in immune tissues, mediates the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 may represent a new therapeutic target for B cell malignancies on continued signaling via the B cell antigen receptor.

Molekulargewicht: Predicted: 30 kDa

Observed: 30 kDa

Gen-ID: 84329

NCBI Accession: NP_115745

UniProt: Q96D96

Pathways: Proton Transport