CACNA1A Antikörper (AA 1401-1500) (HRP)

Produktnummer ABIN751312

Produktdetails anti-CACNA1A Antikörper (HRP)

Target: CACNA1A (Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))

Bindungsspezifität: AA 1401-1500

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1A Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CACNA1A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CACNA1A

Target: CACNA1A (Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))

Andere Bezeichnung: CACNA1A/Cav2.1 (CACNA1A Produkte)

Synonyme: cav2.1 antikoerper, cacna-a antikoerper, ca(v)2.1 antikoerper, cacna1a antikoerper, si:ch211-237k17.1 antikoerper, BccA1 antikoerper, Cav2.1 antikoerper, rbA-1 antikoerper, APCA antikoerper, BI antikoerper, CACNL1A4 antikoerper, CAV2.1 antikoerper, EA2 antikoerper, FHM antikoerper, HPCA antikoerper, MHP antikoerper, MHP1 antikoerper, SCA6 antikoerper, Caca1a antikoerper, Cacnl1a4 antikoerper, Ccha1a antikoerper, alpha1A antikoerper, la antikoerper, leaner antikoerper, nmf352 antikoerper, rkr antikoerper, rocker antikoerper, tg antikoerper, tottering antikoerper, CACH4 antikoerper, CACN3 antikoerper, calcium channel, voltage-dependent, P/Q type, alpha 1A subunit S homeolog antikoerper, calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a antikoerper, calcium voltage-gated channel subunit alpha1 A antikoerper, calcium channel, voltage-dependent, P/Q type, alpha 1A subunit antikoerper, P/Q-type voltage-gated calcium channel alpha1A subunit ChCaChA1A antikoerper, cacna1a.S antikoerper, cacna1aa antikoerper, CACNA1A antikoerper, Cacna1a antikoerper, LOC395892 antikoerper

Hintergrund:

Synonyms: APCA, BI, Brain calcium channel 1, Brain calcium channel I, Cach4, Cacn3, Cacna1a, Cacnl1a4, Calcium channel alpha 1A subunit, Calcium channel L type alpha 1 polypeptide, Calcium channel L type alpha-1 polypeptide isoform 4, Calcium channel voltage dependent, P/Q type alpha 1A subunit, CAV2.1, EA2, FHM, HPCA, MHP, MHP1, RAT brain class A, RBA-I, SCA6, Voltage-dependent P/Q-type calcium channel alpha-1A subunit, Voltage-gated calcium channel alpha subunit Cav2.1, CAC1A_HUMAN.

Background: Cav2.1 is a voltage-sensitive calcium channels (VSCC) which belongs to the calcium channel alpha-1 subunit family. Cav2.1 mediates the entry of calcium ions into excitable cells and is also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Cav2.1 (isoform alpha-1A) gives rise to P and/or Q-type calcium currents. Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.

Gen-ID: 773

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process