CACNA1A Produkte
(Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))
Kategorien
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2. This gene also exhibits polymorphic variation due to (CAG)n-repeats. Multiple transcript variants encoding different isoforms have been found for this gene. In one set of transcript variants, the (CAG)n-repeats occur in the 3' UTR, and are not associated with any disease. But in another set of variants, an insertion extends the coding region to include the (CAG)n-repeats which encode a polyglutamine tract. Expansion of the (CAG)n-repeats from the normal 4-16 to 21-28 in the coding region is associated with spinocerebellar ataxia 6. [provided by RefSeq, Mar 2010].
antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.
Ausgewählte CACNA1A Kategorien
CACNA1A Antikörper
High quality antibodies with extensive validation data.
CACNA1A ELISA Kits
Reliable ELISA kits for a wide range of species.
CACNA1A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CACNA1A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7175608
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN306878
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN6243080
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene CACNA1A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965321
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965320
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1167089
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CACNA1A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3090203
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3121194
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3090205
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CACNA1A Produkten
: "The Cav2.1/alpha1A (P/Q-type) voltage-dependent calcium channel mediates inhibitory neurotransmission onto mouse cerebellar Purkinje cells." in: The European journal of neuroscience, Vol. 13, Issue 10, pp. 1902-12, (2001) (PubMed).: "Vascular smooth muscle cells express the alpha(1A) subunit of a P-/Q-type voltage-dependent Ca(2+)Channel, and It is functionally important in renal afferent arterioles." in: Circulation research, Vol. 87, Issue 10, pp. 896-902, (2000) (PubMed).
Synonyme und alternative Namen zu CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit S homeolog (cacna1a.S), calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a (cacna1aa), calcium voltage-gated channel subunit alpha1 A (CACNA1A), calcium voltage-gated channel subunit alpha1 A (Cacna1a), calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (Cacna1a), P/Q-type voltage-gated calcium channel alpha1A subunit ChCaChA1A (LOC395892), alpha1A, APCA, BccA1, BI, ca(v)2.1, Caca1a, CACH4, CACN3, cacna-a, cacna1a, CACNL1A4, Cacnl1a4, cav2.1, Cav2.1, CAV2.1, Ccha1a, EA2, FHM, HPCA, la, leaner, MHP, MHP1, nmf352, rbA-1, rkr, rocker, SCA6, si:ch211-237k17.1, tg, totteringBezeichner auf Proteinebene für CACNA1A
- calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
- voltage-dependent calcium ion channel alpha subunit
- ZfCav2.1
- BI
- RBA-I
- brain calcium channel 1
- brain calcium channel I
- brain class A
- calcium channel alpha 1A
- calcium channel, L type, alpha-1 polypeptide
- calcium channel, voltage-dependent, alpha 1A subunit
- voltage-dependent P/Q-type calcium channel subunit alpha-1A
- voltage-gated calcium channel subunit alpha Cav2.1
- P/Q-type calcium channel alpha1A subunit
- calcium channel, P/Q type, alpha 1A
- calcium channel, alpha 1A subunit
- voltage-gated calcium channel alpha 1A subunit
- calcium channel BI-1
- calcium channel BI-2
Sie sind hier:
