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CACNA2D1 Produkte

(Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].

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Ausgewählte CACNA2D1 Kategorien

CACNA2D1 Antikörper

High quality antibodies with extensive validation data.

CACNA2D1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CACNA2D1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (2)
Kat. Nr. ABIN7175577
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, FACS
Validierungen
  • (2)
Kat. Nr. ABIN652644
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN190770
Menge 100 μg
Datenblatt Datenblatt

Empfohlene CACNA2D1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3098607
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3131233
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3090543
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CACNA2D1 Produkten

Cui, Chu, Xu, Chen, Gao, Feng, Hu, Yang, Du, Zhang, Mao-Ying, Mi, Wang: "Calcium Channel α2δ1 Subunit Mediates Secondary Orofacial Hyperalgesia Through PKC-TRPA1/Gap Junction Signaling." in: The journal of pain : official journal of the American Pain Society, (2019) (PubMed).

Chintalapudi, Maria, Di Wang, Bailey, Hysi, Wiggs, Williams, Jablonski: "Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility." in: Nature communications, Vol. 8, Issue 1, pp. 1755, (2018) (PubMed).

Yang, Yang, Yang, Li, Wang, Li, Lu, Yu, Fu, He, Sun, Wang, Chen: "Gabapentinoid Insensitivity after Repeated Administration is Associated with Down-Regulation of the α(2)δ-1 Subunit in Rats with Central Post-Stroke Pain Hypersensitivity." in: Neuroscience bulletin, Vol. 32, Issue 1, pp. 41-50, (2016) (PubMed).

Yu, Holm, Goscinski, Trope, Nesland, Suo: "Prognostic and clinicopathological significance of Cacna2d1 expression in epithelial ovarian cancers: a retrospective study." in: American journal of cancer research, Vol. 6, Issue 9, pp. 2088-2097, (2016) (PubMed).

Tétreault, Bourdin, Briot, Segura, Lesage, Fiset, Parent: "Identification of Glycosylation Sites Essential for Surface Expression of the CaVα2δ1 Subunit and Modulation of the Cardiac CaV1.2 Channel Activity." in: The Journal of biological chemistry, Vol. 291, Issue 9, pp. 4826-43, (2016) (PubMed).

Han, Du, Zhao, Li, Chen, Zhang, Liu, Suo, Bian, Xing, Zhang: "PBX3 is targeted by multiple miRNAs and is essential for liver tumour-initiating cells." in: Nature communications, Vol. 6, pp. 8271, (2015) (PubMed).

Bannister, Thomas-Gatewood, Neeb, Adebiyi, Cheng, Jaggar: "Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cells." in: The Journal of biological chemistry, Vol. 286, Issue 17, pp. 15058-66, (2011) (PubMed).

Horiuchi-Hirose, Kashihara, Nakada, Kurebayashi, Shimojo, Shibazaki, Sheng, Yano, Hirose, Hongo, Sakurai, Moriizumi, Ueda, Yamada: "Decrease in the density of t-tubular L-type Ca2+ channel currents in failing ventricular myocytes." in: American journal of physiology. Heart and circulatory physiology, Vol. 300, Issue 3, pp. H978-88, (2011) (PubMed).

Neely, Hess, Costigan, Keene, Goulas, Langeslag, Griffin, Belfer, Dai, Smith, Diatchenko, Gupta, Xia, Amann, Kreitz, Heindl-Erdmann, Wolz, Ly, Arora, Sarangi, Dan, Novatchkova, Rosenzweig, Gibson et al.: "A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. ..." in: Cell, Vol. 143, Issue 4, pp. 628-38, (2010) (PubMed).

Tishkoff, Nibbelink, Holmberg, Dandu, Simpson: "Functional vitamin D receptor (VDR) in the t-tubules of cardiac myocytes: VDR knockout cardiomyocyte contractility." in: Endocrinology, Vol. 149, Issue 2, pp. 558-64, (2008) (PubMed).

Synonyme und alternative Namen zu CACNA2D1

calcium voltage-gated channel auxiliary subunit alpha2delta 1 (CACNA2D1), calcium channel, voltage-dependent, alpha 2/delta subunit 1 (cacna2d1), calcium voltage-gated channel auxiliary subunit alpha2delta 1 (cacna2d1), calcium voltage-gated channel auxiliary subunit alpha2delta 1 (Cacna2d1), calcium channel, voltage-dependent, alpha2/delta subunit 1 (Cacna2d1), Ca(v)alpha2delta1, CACNA2, Cacna2, CACNA2D1, CACNL2A, CCHL2A, Cchl2a, CCHLA2, DHSCCA, DKFZp469K2211

Bezeichner auf Proteinebene für CACNA2D1

  • calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • voltage-dependent calcium channel subunit alpha-2/delta-1-like
  • calcium channel, L type, alpha 2 polypeptide
  • dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit
  • voltage-dependent calcium channel subunit alpha-2/delta-1
  • voltage-gated calcium channel subunit alpha-2/delta-1
  • dihydropryridine-sensitive calcium channel alpha-2 subunit
  • dihydropyridine-sensitive calcium channel alpha 2
  • Calcium channel subunit alpha 2 delta (dihydropyridine - sensitive L-type)
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