NR1D1 Antikörper (pSer55, pSer59)

Produktnummer ABIN745553

Produktdetails anti-NR1D1 Antikörper

Target: NR1D1 (Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1))

Bindungsspezifität: pSer55, pSer59

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR1D1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: These phosphorylation sites are homologous among the listed cross-reactive species.

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human REV-ERB alpha around the phosphorylation site of Ser55/59

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NR1D1

Target: NR1D1 (Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1))

Andere Bezeichnung: NR1D1 + (NR1D1 Produkte)

Synonyme: MGC82865 antikoerper, MGC82881 antikoerper, Eip75B antikoerper, EAR1 antikoerper, THRA1 antikoerper, THRAL antikoerper, ear-1 antikoerper, hRev antikoerper, A530070C09Rik antikoerper, R75201 antikoerper, REV-ERBAALPHA antikoerper, nuclear receptor subfamily 1 group D member 1 L homeolog antikoerper, nuclear receptor subfamily 1, group d, member 1 antikoerper, nuclear receptor subfamily 1 group D member 1 antikoerper, nuclear receptor subfamily 1, group D, member 1 antikoerper, nr1d1.L antikoerper, nr1d1 antikoerper, NR1D1 antikoerper, Nr1d1 antikoerper

Hintergrund:

Synonyms: EAR1, hRev, THRA1, THRAL, ear-1, Nuclear receptor subfamily 1 group D member 1, Rev-erbA-alpha, V-erbA-related protein 1, NR1D1

Background: This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes. [provided by RefSeq, Jan 2013]

Gen-ID: 9572

UniProt: P20393

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha