NR1D1 Antikörper

Produktnummer ABIN700854

Produktdetails anti-NR1D1 Antikörper

Target: NR1D1 (Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR1D1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NR1D1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Referenzen für anti-NR1D1 Antikörper (ABIN700854)

Zhao, Li, Wei, Savage, Zhou, Ma: "Ketamine administered to pregnant rats in the second trimester causes long-lasting behavioral disorders in offspring." in: Neurobiology of disease, Vol. 68, pp. 145-55, (2014) (PubMed).

Details zu NR1D1

Target: NR1D1 (Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1))

Andere Bezeichnung: NR1D1 (NR1D1 Produkte)

Synonyme: MGC82865 antikoerper, MGC82881 antikoerper, Eip75B antikoerper, EAR1 antikoerper, THRA1 antikoerper, THRAL antikoerper, ear-1 antikoerper, hRev antikoerper, A530070C09Rik antikoerper, R75201 antikoerper, REV-ERBAALPHA antikoerper, nuclear receptor subfamily 1 group D member 1 L homeolog antikoerper, nuclear receptor subfamily 1, group d, member 1 antikoerper, nuclear receptor subfamily 1 group D member 1 antikoerper, nuclear receptor subfamily 1, group D, member 1 antikoerper, nr1d1.L antikoerper, nr1d1 antikoerper, NR1D1 antikoerper, Nr1d1 antikoerper

Hintergrund:

Synonyms: EAR-1, EAR1, ERBA-RELATED 1, hRev, Nr1d1, NR1D1_HUMAN, Nuclear Receptor Rev-ErbA Alpha, Nuclear receptor subfamily 1 group D member 1, Orphan nuclear receptor NR1D1, Rev erbAalpha, Rev erbalpha, Rev-erbA-alpha, Rev-ErbAalpha, REV-ERBalpha, THRA1, THRAL, Thyroid hormone receptor alpha-like, Thyroid hormone receptor, alpha like, V-erbA related protein EAR-1, V-erbA-related protein 1.

Background: NR1D1, a NR1 Thyroid Hormone-Like Receptor, is encoded by the same genomic locus as, but transcribed from the opposite strand of, Thyroid Hormone Receptor Alpha (TR Alpha). NR1D1 is a target of Nuclear Receptor ROR Alpha and a transcription regulator that has been shown to affect myocyte differentiation, adipogenesis, and lipoprotein metabolism. Mice lacking NR1D1 show abnormal postnatal cerebellar development. NR1D1 expression has been documented in human skeletal muscle and a variety of mouse and rat tissues. ESTs have been isolated from human tissue libraries, including cancerous adrenal, blood, brain, breast, colon, duodenum, fetus, head/neck, kidney, lung, skeletal muscle, skin, synovium, uterus, normal brain, breast, colon, eye, heart, pancreas, pituitary, prostate, skeletal muscle, skin, testis and thyroid.

Molekulargewicht: 68kDa

Gen-ID: 9572

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha