TNFSF14 Antikörper (AA 141-240) (PE)

Produktnummer ABIN740635

Produktdetails anti-TNFSF14 Antikörper (PE)

Target: TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))

Bindungsspezifität: AA 141-240

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFSF14 Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TNFSF14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-TNFSF14 Antikörper (PE) (ABIN740635)

Sibilano, Gaudenzio, DeGorter, Reber, Hernandez, Starkl, Zurek, Tsai, Zahner, Montgomery, Roers, Kronenberg, Yu, Galli: "A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice." in: Nature communications, Vol. 7, pp. 13696, (2016) (PubMed).

Details zu TNFSF14

Target: TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))

Andere Bezeichnung: TNFSF14 (TNFSF14 Produkte)

Synonyme: TNFSF14 antikoerper, CD258 antikoerper, HVEML antikoerper, LIGHT antikoerper, LTg antikoerper, TR2 antikoerper, HVEM-L antikoerper, Ly113 antikoerper, TNF superfamily member 14 antikoerper, tumor necrosis factor (ligand) superfamily, member 14 antikoerper, TNFSF14 antikoerper, Tnfsf14 antikoerper

Hintergrund:

Synonyms: LTg, TR2, CD258, HVEML, LIGHT, Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, HVEM-L, Herpesvirus entry mediator ligand, TNFSF14, UNQ391/PRO726

Background: Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.

Gen-ID: 8740

UniProt: O43557

Pathways: Cancer Immune Checkpoints