KCNJ11 Antikörper (AA 301-390) (Biotin)
-
- Target Alle KCNJ11 Antikörper anzeigen
- KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
-
Bindungsspezifität
- AA 301-390
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser KCNJ11 Antikörper ist konjugiert mit Biotin
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Cow,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Kir62
- Isotyp
- IgG
- Top Product
- Discover our top product KCNJ11 Primärantikörper
-
-
- Applikationshinweise
-
WB 1:300-5000
IHC-P 1:200-400 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
-
- Target
- KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
- Andere Bezeichnung
- Kir6.2 (KCNJ11) (KCNJ11 Produkte)
- Synonyme
- kir6.2 antikoerper, Kir6.2 antikoerper, mBIR antikoerper, BIR antikoerper, HHF2 antikoerper, IKATP antikoerper, KIR6.2 antikoerper, PHHI antikoerper, TNDM3 antikoerper, potassium voltage-gated channel subfamily J member 11 antikoerper, potassium inwardly-rectifying channel, subfamily J, member 11 antikoerper, potassium inwardly rectifying channel, subfamily J, member 11 antikoerper, KCNJ11 antikoerper, kcnj11 antikoerper, Kcnj11 antikoerper
- Hintergrund
-
Synonyms: ATP sensitive inward rectier potassium channel 11, Beta cell inward rectier subunit, mBIR, BIR, HHF 2, HHF2, IKATP, Inward rectier K+ channel Kir6.2, Inwardly rectying potassium channel KIR6.2, IRK 11, IRK11, KCNJ11, Kir 6.2, Kir6.2, MGC133230, PHHI, Potassium channel, inwardly rectying subfamily J member 11, Potassium inwardly rectying channel J11, TNDM 3, TNDM3, IRK11_HUMAN.
Background: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq]
- Gen-ID
- 3767
- UniProt
- Q14654
- Pathways
- Negative Regulation of Hormone Secretion
-