KCNJ11 Antikörper (AA 172-390)

Produktnummer ABIN7145021

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch KCNJ11 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für KCNJ11 Antikörper (AA 172-390) (ABIN7145021)

Target: KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNJ11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-KCNJ11 Antikörper

Bindungsspezifität: AA 172-390

Verwendungszweck: KCNJ11 Antibody

Kreuzreaktivität: Maus

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Human ATP-sensitive inward rectifier potassium channel 11 protein (172-390AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu KCNJ11

Target: KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))

Andere Bezeichnung: KCNJ11

Hintergrund:

Background: This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.

Aliases: KCNJ11 antibody, ATP-sensitive inward rectifier potassium channel 11 antibody, IKATP antibody, Inward rectifier K(+) channel Kir6.2 antibody, Potassium channel antibody, inwardly rectifying subfamily J member 11 antibody

UniProt: Q14654

Pathways: Negative Regulation of Hormone Secretion