SLC8A1 Antikörper (AA 801-900) (Cy3)

Produktnummer ABIN731201

Produktdetails anti-SLC8A1 Antikörper (Cy3)

Target: SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))

Bindungsspezifität: AA 801-900

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC8A1 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Horse,Chicken,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NCX1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SLC8A1

Target: SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))

Andere Bezeichnung: NCX1/SLC8A1 (SLC8A1 Produkte)

Synonyme: NCX1 antikoerper, AI852629 antikoerper, AV344025 antikoerper, D930008O12Rik antikoerper, Ncx1 antikoerper, Ncx antikoerper, SLC8A1 antikoerper, ncx1n antikoerper, solute carrier family 8 member A1 antikoerper, solute carrier family 8 (sodium/calcium exchanger), member 1 antikoerper, solute carrier family 8 (sodium/calcium exchanger), member 1b antikoerper, sodium/calcium exchanger 1 antikoerper, SLC8A1 antikoerper, Slc8a1 antikoerper, slc8a1b antikoerper, Tsp_07038 antikoerper

Hintergrund:

Synonyms: Na+/Ca2+exchanger 1, CNC, DKFZp779F0871, MGC119581 , FLJ37694, FLJ43417, Na+/Ca2+ exchange protein 1, Na+/Ca2+ exchanger, NCX 1, NCX, SLC8A1, SLC8A1 protein , Sodium Calcium Exchanger, Sodium/calcium exchanger 1, Solute carrier family 8 member 1.

Background: In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma(plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM].

Gen-ID: 6546

Pathways: Myometrial Relaxation and Contraction