SLC8A1 Antikörper (AA 250-520)

Produktnummer ABIN6148050

Produktdetails anti-SLC8A1 Antikörper

Target: SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))

Bindungsspezifität: AA 250-520

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC8A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: WVADRRLLFY KYVYKRYRAG KQRGMIIEHE GDRPSSKTEI EMDGKVVNSH VENFLDGALV LEVDERDQDD EEARREMARI LKELKQKHPD KEIEQLIELA NYQVLSQQQK SRAFYRIQAT RLMTGAGNIL KRHAADQARK AVSMHEVNTE VTENDPVSKI FFEQGTYQCL ENCGTVALTI IRRGGDLTNT VFVDFRTEDG TANAGSDYEF TEGTVVFKPG DTQKEIRVGI IDDDIFEEDE NFLVHLSNVK VSSEASEDGI LEANHVSTLA C

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-520 of human SLC8A1 (NP_066920.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SLC8A1

Target: SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))

Andere Bezeichnung: SLC8A1 (SLC8A1 Produkte)

Synonyme: NCX1 antikoerper, AI852629 antikoerper, AV344025 antikoerper, D930008O12Rik antikoerper, Ncx1 antikoerper, Ncx antikoerper, SLC8A1 antikoerper, ncx1n antikoerper, solute carrier family 8 member A1 antikoerper, solute carrier family 8 (sodium/calcium exchanger), member 1 antikoerper, solute carrier family 8 (sodium/calcium exchanger), member 1b antikoerper, sodium/calcium exchanger 1 antikoerper, SLC8A1 antikoerper, Slc8a1 antikoerper, slc8a1b antikoerper, Tsp_07038 antikoerper

Hintergrund: In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.,SLC8A1,NCX1,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Calcium Signaling,Cardiovascular,Hypoxia,Heart,Contractility,SLC8A1

Molekulargewicht: 104 kDa/107 kDa/108 kDa

Gen-ID: 6546

UniProt: P32418

Pathways: Myometrial Relaxation and Contraction