TTF-1 / Thyroid-Specific TF (AA 195-245) Antikörper (Cy5)

Details zu Produkt Nr. ABIN728717, Anbieter: Anmelden zum Anzeigen
Antigen
Epitop
AA 195-245
7
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
22
10
9
1
1
1
1
Wirt
Kaninchen
12
10
Klonalität
Polyklonal
Konjugat
Cy5
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
17
7
5
5
5
2
1
Optionen
Hersteller
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Immunogen KLH conjugated synthetic peptide derived from human TTF-1
Isotyp IgG
Reinigung Purified by Protein A.
Hintergrund

Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity).

Subcellular location: Nucleus

Synonyms: BCH, BHC, NK-2, TEBP, TTF1, NKX2A, T/EBP, TITF1, TTF-1, NKX2.1, Homeobox protein Nkx-2.1, Homeobox protein NK-2 homolog A, Thyroid nuclear factor 1, Thyroid transcription factor 1, Thyroid-specific enhancer-binding protein, NKX2-1

Gen-ID 7080
UniProt P43699
Applikationshinweise FCM 1:20-100
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
Produkt verwendet in: Vadasz, Jensen, Moncada, Girard, Zhang, Blanchette, Finck: "Second and third trimester amniotic fluid mesenchymal stem cells can repopulate a de-cellularized lung scaffold and express lung markers." in: Journal of pediatric surgery, Vol. 49, Issue 11, pp. 1554-63, 2014 (PubMed). (Probematerial (Species): Human).

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