The mouse monoclonal antibody AYP1 recognizes an epitope within the extracellular part of CLEC2, a transmembrane glycoprotein expressed on activated plateles and on platelet microparticles.
Aufreinigung
Purified by protein-A affinity chromatography.
Immunogen
A recombinant extracellular domain of human CLEC2 (amino acids 68-229)
1810061I13Rik antikoerper, CLEC2 antikoerper, CLEC2B antikoerper, PRO1384 antikoerper, QDED721 antikoerper, Clec-2 antikoerper, Clec2 antikoerper, CLEC1B antikoerper, RGD1563517 antikoerper, CLEC9A antikoerper, C-type lectin domain family 1 member B antikoerper, C-type lectin domain family 1, member b antikoerper, C-type lectin domain family 1, member B antikoerper, CLEC1B antikoerper, Clec1b antikoerper
Substanzklasse
Viral Protein
Hintergrund
C-type lectin domain family 1 member B,CLEC2 (C-type lectin-like receptor 2) functions as a platelet receptor for the lymphatic endothelial marker, PDPN, and mediates platelet activation. Besides platelets, it can be found on myeloid cells and NK cells. CLEC2 functions also as an attachment factor for HIV-1 and facilitates its capture by platelets. Platelet-aggregating snake venom protein rhodocytin also binds to CLEC2.,CLEC1B, CLEC2B, PRO1384, QDED721