The mouse monoclonal antibody AYP1 recognizes an epitope within the extracellular part of CLEC2, a transmembrane glycoprotein expressed on activated plateles and on platelet microparticles.
Aufreinigung
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Immunogen
A recombinant extracellular domain of human CLEC2 (amino acids 68-229)
CLEC1B
Reaktivität: Human
WB
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
1810061I13Rik antikoerper, CLEC2 antikoerper, CLEC2B antikoerper, PRO1384 antikoerper, QDED721 antikoerper, Clec-2 antikoerper, Clec2 antikoerper, CLEC1B antikoerper, RGD1563517 antikoerper, CLEC9A antikoerper, C-type lectin domain family 1 member B antikoerper, C-type lectin domain family 1, member b antikoerper, C-type lectin domain family 1, member B antikoerper, CLEC1B antikoerper, Clec1b antikoerper
Substanzklasse
Viral Protein
Hintergrund
C-type lectin domain family 1 member B,CLEC2 (C-type lectin-like receptor 2) functions as a platelet receptor for the lymphatic endothelial marker, PDPN, and mediates platelet activation. Besides platelets, it can be found on myeloid cells and NK cells. CLEC2 functions also as an attachment factor for HIV-1 and facilitates its capture by platelets. Platelet-aggregating snake venom protein rhodocytin also binds to CLEC2.,CLEC1B, CLEC2B, PRO1384, QDED721