HVEM Antikörper

Produktnummer ABIN7505890

Produktdetails anti-HVEM Antikörper

Target: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HVEM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Verwendungszweck: Anti-Hu CD270 Purified

Spezifität: The mouse monoclonal antibody CW10 recognizes an extracellular epitope on CD270, a type I transmembrane protein expressed on resting T cells, monocytes, and immature dendritic cells.

Aufreinigung: Purified by protein-A affinity chromatography.

Immunogen: recombinant human CD270

Klon: CW10

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-5 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu HVEM

Target: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Andere Bezeichnung: CD270 (TNFRSF14 Produkte)

Synonyme: ATAR antikoerper, CD270 antikoerper, HVEA antikoerper, HVEM antikoerper, LIGHTR antikoerper, TR2 antikoerper, Atar antikoerper, HveA antikoerper, Hvem antikoerper, Tnfrs14 antikoerper, TNF receptor superfamily member 14 antikoerper, tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) antikoerper, Tnfrsf14 antikoerper, TNFRSF14 antikoerper

Substanzklasse: Viral Protein

Hintergrund: TNF receptor superfamily member 14,CD270 is a type I transmembrane protein of the TNFR superfamily, which is expressed on resting T cells, monocytes, and immature dendritic cells. Its ligands, CD258 and CD272, differ in effect on CD270 signaling. Whereas binding to CD258 provides a costimulatory signal, binding to CD272 gives to the cell an inhibitory signal. CD270 also is recognized by herpes simplex glycoprotein D. CD258-CD270 interaction and signaling is implicated in macrophage-derived foam cell-mediated development of atherosclerotic lesions.,TNFRSF14, TR2, ATAR, HVEA, HVEM, LIGHTR

Gen-ID: 8764

UniProt: Q92956

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints