SRD5A2 Antikörper

Produktnummer ABIN720146

Produktdetails anti-SRD5A2 Antikörper

Target: SRD5A2 (Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRD5A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: 83 % sequence similarity with 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SRD5A2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:100-1000, IHC-P: 1:100-500, IF(IHC-P): 1:50-200
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Referenzen für anti-SRD5A2 Antikörper (ABIN720146)

Tanaka, Miki, Hashimoto, Takagi, Doe, Li, Yaegashi, Suzuki, Ito: "The role of 5α-reductase type 1 associated with intratumoral dihydrotestosterone concentrations in human endometrial carcinoma." in: Molecular and cellular endocrinology, Vol. 401, pp. 56-64, (2015) (PubMed).

Details zu SRD5A2

Target: SRD5A2 (Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2))

Andere Bezeichnung: Srd5a2 (SRD5A2 Produkte)

Synonyme: S5AR 2 antikoerper, 5ART2 antikoerper, SRD5alpha2 antikoerper, SRD5A2 antikoerper, Srd5a2 antikoerper, CH73-233A22.6 antikoerper, wu:fk70d02 antikoerper, zgc:109942 antikoerper, zgc:112208 antikoerper, zgc:112455 antikoerper, steroid 5 alpha-reductase 2 antikoerper, steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) antikoerper, 3-oxo-5-alpha-steroid 4-dehydrogenase 2 antikoerper, steroid-5-alpha-reductase, alpha polypeptide 2a antikoerper, steroid-5-alpha-reductase, alpha polypeptide 2b antikoerper, SRD5A2 antikoerper, Srd5a2 antikoerper, srd5a2 antikoerper, LOC100125532 antikoerper, srd5a2a antikoerper, srd5a2b antikoerper

Hintergrund:

Synonyms: 5 alpha SR2, EC, SR type 2, Steroid 5 alpha reductase 2, 3 oxo 5 alpha steroid 4 dehydrogenase 2, 3-oxo-5-alpha-steroid 4-dehydrogenase 2, 5 alpha-SR2, 5ART2, e II 5 alpha reductase, EC, MGC138457, Micropenis, included, S5A2_HUMAN, S5AR 2, SR type 2, SRD5A2, Steroid 5 alpha reductase 2, Steroid 5-alpha-reductase 2, Steroid-5-alpha-reductase, alpha polypeptide 2 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2, Type II 5-alpha reductase.

Background: Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.

Gen-ID: 6716

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis