ATP2B3 Antikörper (C-Term)

Produktnummer ABIN7468011

Produktdetails anti-ATP2B3 Antikörper

Target: ATP2B3 (ATPase, Ca++ Transporting, Plasma Membrane 3 (ATP2B3))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP2B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human ATP2B3 / PMCA3 ATPase. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: U87-MG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu ATP2B3

Target: ATP2B3 (ATPase, Ca++ Transporting, Plasma Membrane 3 (ATP2B3))

Andere Bezeichnung: ATPase plasma membrane Ca2+ transporting 3 (ATP2B3 Produkte)

Synonyme: PMCA3 antikoerper, PMCA3a antikoerper, SCAX1 antikoerper, atp2b3 antikoerper, pmca3a antikoerper, zgc:92885 antikoerper, 6430519O13Rik antikoerper, Pmca3 antikoerper, ATPase plasma membrane Ca2+ transporting 3 antikoerper, ATPase, Ca++ transporting, plasma membrane 3a antikoerper, ATPase, Ca++ transporting, plasma membrane 3 antikoerper, plasma membrane calcium-transporting ATPase 2 antikoerper, ATP2B3 antikoerper, atp2b3a antikoerper, Atp2b3 antikoerper, atp2b3 antikoerper, LOC100639471 antikoerper

Hintergrund:

Synonyms: ATPase plasma membrane Ca2+ transporting 3 , CFAP39 , CLA2 , OPCA , PMCA3 , PMCA3a , SCAX1

Background: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 3. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Molekulargewicht: 134 kDa

Gen-ID: 492

UniProt: Q16720

Pathways: Ribonucleoside Biosynthetic Process