ATP2B1 Antikörper

Produktnummer ABIN7468010

Produktdetails anti-ATP2B1 Antikörper

Target: ATP2B1 (ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP2B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PMCA1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HeLa Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu ATP2B1

Target: ATP2B1 (ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))

Andere Bezeichnung: ATPase plasma membrane Ca2+ transporting 1 (ATP2B1 Produkte)

Synonyme: PMCA1 antikoerper, PMCA1kb antikoerper, PMCA antikoerper, 2810442I22Rik antikoerper, E130111D10Rik antikoerper, Pmca1 antikoerper, ATP2B1 antikoerper, DKFZp459A1127 antikoerper, atp2b1 antikoerper, Pmca1a antikoerper, Pmca1b antikoerper, Pmca1c antikoerper, pmca1 antikoerper, pmca1a antikoerper, sb:cb801 antikoerper, si:dkey-18o7.1 antikoerper, wu:fe47b06 antikoerper, wu:fi41d01 antikoerper, atp2b1b antikoerper, ATPase plasma membrane Ca2+ transporting 1 antikoerper, ATPase, Ca++ transporting, plasma membrane 1 antikoerper, plasma membrane calcium-transporting ATPase 2 antikoerper, ATPase, Ca++ transporting, plasma membrane 1a antikoerper, ATPase, Ca++ transporting, plasma membrane 1 L homeolog antikoerper, ATP2B1 antikoerper, Atp2b1 antikoerper, atp2b1 antikoerper, LOC100180580 antikoerper, atp2b1a antikoerper, atp2b1.L antikoerper

Hintergrund:

Synonyms: ATPase plasma membrane Ca2+ transporting 1 , PMCA1 , PMCA1kb

Background: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Molekulargewicht: 139 kDa

Gen-ID: 490

UniProt: P20020

Pathways: Ribonucleoside Biosynthetic Process