ATP2B1 Antikörper (AA 351-450)

Produktnummer ABIN1714863

Produktdetails anti-ATP2B1 Antikörper

Target: ATP2B1 (ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))

Bindungsspezifität: AA 351-450

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP2B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Hund, Human

Homologie: Mouse,Rat,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PMCA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ATP2B1

Target: ATP2B1 (ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))

Andere Bezeichnung: PMCA1 (ATP2B1 Produkte)

Synonyme: PMCA1 antikoerper, PMCA1kb antikoerper, PMCA antikoerper, 2810442I22Rik antikoerper, E130111D10Rik antikoerper, Pmca1 antikoerper, ATP2B1 antikoerper, DKFZp459A1127 antikoerper, atp2b1 antikoerper, Pmca1a antikoerper, Pmca1b antikoerper, Pmca1c antikoerper, pmca1 antikoerper, pmca1a antikoerper, sb:cb801 antikoerper, si:dkey-18o7.1 antikoerper, wu:fe47b06 antikoerper, wu:fi41d01 antikoerper, atp2b1b antikoerper, ATPase plasma membrane Ca2+ transporting 1 antikoerper, ATPase, Ca++ transporting, plasma membrane 1 antikoerper, plasma membrane calcium-transporting ATPase 2 antikoerper, ATPase, Ca++ transporting, plasma membrane 1a antikoerper, ATPase, Ca++ transporting, plasma membrane 1 L homeolog antikoerper, ATP2B1 antikoerper, Atp2b1 antikoerper, atp2b1 antikoerper, LOC100180580 antikoerper, atp2b1a antikoerper, atp2b1.L antikoerper

Hintergrund:

Synonyms: ATP2B1, AT2B1_HUMAN, ATP2B1, ATPase Ca++ transporting plasma membrane 1, Plasma membrane calcium ATPase 1, Plasma membrane calcium ATPase isoform 1, Plasma membrane calcium pump isoform 1, Plasma membrane calcium transporting ATPase 1, Plasma membrane calcium-transporting ATPase 1, PMCA 1, PMCA1.

Background: Plasma membrane-type Ca2+-ATPases (PMCAs) mediate the export of bivalent calcium ions from eukaryotic cells. As members of the P class of ion-motive ATPases, PMCAs are a functionally diverse group of proteins that are derived from alternatively spliced transcripts originating from at least four distinct genes. The expression of different PMCA isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, and with respect to the physiological needs of specific cell and tissue types. Spatial and temporal rates of resting intracellular Ca2+ concentrations and Ca2+ signaling in eukaryotic cells are dependent on the array of PMCA isoforms that are expressed in concert with the rate of Ca2+ export. PMCA1 (ATP2B1) is a ubiquitously expressed form of the PMCA calcium exporter family.

Gen-ID: 3820

UniProt: P20020

Pathways: Ribonucleoside Biosynthetic Process