POLD2 Antikörper (AA 419-469)

Produktnummer ABIN7455022

Produktdetails anti-POLD2 Antikörper

Target: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Bindungsspezifität: AA 419-469

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-PolD2 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 419 and 469

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu POLD2

Target: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Andere Bezeichnung: PolD2 (POLD2 Produkte)

Synonyme: 50kDa antikoerper, p50 antikoerper, po1D2 antikoerper, cdc1 antikoerper, si:dz150f13.3 antikoerper, zgc:55633 antikoerper, zgc:77043 antikoerper, DNA polymerase delta 2, accessory subunit antikoerper, polymerase (DNA directed), delta 2, regulatory subunit antikoerper, polymerase (DNA directed), delta 2, accessory subunit L homeolog antikoerper, POLD2 antikoerper, Pold2 antikoerper, pold2.L antikoerper, pold2 antikoerper

Hintergrund: Background: DNA polymerase delta subunit 2 (PolD2) is the 50- kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. PolD2 is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA [taken from NCBI Entrez Gene (Gene ID: 5425)].

Gen-ID: 5425

NCBI Accession: NP_001120690

UniProt: P49005

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA