PSMD3 Antikörper (AA 1-50)

Produktnummer ABIN7454966

Produktdetails anti-PSMD3 Antikörper

Target: PSMD3 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 3 (PSMD3))

Bindungsspezifität: AA 1-50

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-PSMD3 Antibody, Affinity Purified

Homologie: Bovine

Aufreinigung: Affinity Purified

Immunogen: Between AA 1 and 50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu PSMD3

Target: PSMD3 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 3 (PSMD3))

Andere Bezeichnung: PSMD3 (PSMD3 Produkte)

Synonyme: P58 antikoerper, RPN3 antikoerper, S3 antikoerper, TSTA2 antikoerper, AI255837 antikoerper, AntP91a antikoerper, D11Bwg1349e antikoerper, Psd3 antikoerper, Tstap91a antikoerper, proteasome 26S subunit, non-ATPase 3 antikoerper, proteasome 26S subunit, non-ATPase 3 S homeolog antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 antikoerper, 26S proteasome non-ATPase regulatory subunit 3 antikoerper, PSMD3 antikoerper, psmd3.S antikoerper, Psmd3 antikoerper, rpn-3 antikoerper

Hintergrund: Background: Proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 (PSMD3) is a subunit of the 26S proteasome, a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. PSMD3 is a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid [taken from NCBI Entrez Gene (Gene ID: 5709)].

Gen-ID: 5709

NCBI Accession: NP_002800

UniProt: O43242

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway