TCEB2 Antikörper (AA 68-118)

Produktnummer ABIN7453458

Produktdetails anti-TCEB2 Antikörper

Target: TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))

Bindungsspezifität: AA 68-118

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCEB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-TCEB2 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 68 and 118

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:500 - 1:2,500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu TCEB2

Target: TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))

Andere Bezeichnung: TCEB2 (TCEB2 Produkte)

Synonyme: 0610040H15Rik antikoerper, cb162 antikoerper, wu:fb47e08 antikoerper, ELOB antikoerper, SIII antikoerper, elongin B antikoerper, Elob antikoerper, elob antikoerper, ELOB antikoerper

Hintergrund: Background: TCEB2, also known as Elongin B, is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation [taken from NCBI Entrez Gene (Gene ID: 6923)].

Gen-ID: 6923

NCBI Accession: NP_009039

UniProt: Q15370

Pathways: SARS-CoV-2 Protein Interaktom