RC3H1 Antikörper (C-Term)

Produktnummer ABIN7451565

Produktdetails anti-RC3H1 Antikörper

Target: RC3H1 (Ring Finger and CCCH-Type Domains 1 (RC3H1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RC3H1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-Roquin Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 1075 and C-term

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: 1:1,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu RC3H1

Target: RC3H1 (Ring Finger and CCCH-Type Domains 1 (RC3H1))

Andere Bezeichnung: Roquin (RC3H1 Produkte)

Synonyme: RNF198 antikoerper, ROQUIN antikoerper, RC3H1 antikoerper, si:dkey-192m14.4 antikoerper, 5730557L09Rik antikoerper, Gm551 antikoerper, N28103 antikoerper, mKIAA2025 antikoerper, RGD1563512 antikoerper, rc3h1 antikoerper, ring finger and CCCH-type domains 1 antikoerper, ring finger and CCCH-type domains 1a antikoerper, ring finger and CCCH-type zinc finger domains 1 antikoerper, RING CCCH (C3H) domains 1 antikoerper, ring finger and CCCH-type domains 1 L homeolog antikoerper, RC3H1 antikoerper, rc3h1a antikoerper, Rc3h1 antikoerper, rc3h1.L antikoerper

Hintergrund: Background: The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes and the ligation of ubiquitin to the target protein by E3 enzymes. Roquin is a member of the RING type E3 ubiquitin ligases. Roquin possesses a CCCH zinc-finger found in RNA-binding proteins and is implicated to play a role in the development of autoimmune disease.

Gen-ID: 149041

NCBI Accession: NP_742068

UniProt: Q5TC82

Pathways: Ribonucleoprotein Complex Subunit Organization, Activated T Cell Proliferation