MEK1 Antikörper (AA 343-393)

Produktnummer ABIN7448664

Dieser Anti-MEK1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von MEK1 in IHC. Geeignet für Human.

Kurzübersicht für MEK1 Antikörper (AA 343-393) (ABIN7448664)

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEK1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-MEK1 Antikörper

Bindungsspezifität: AA 343-393

Verwendungszweck: Rabbit anti-MEK1 IHC Antibody, Affinity Purified

Homologie: X. laevis,X. tropicalis,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Pig,Panda,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,White-tufted-ear marmoset,West Indian ocean coelacanth,Duckbill platypus,Small-eared galago,African elephant,Zebra finch,Little brown bat,Island canary,Thirteen-lined ground squirrel,Northern white-cheeked gibbon

Aufreinigung: Affinity Purified

Immunogen: Between AA 343 and 393

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu MEK1

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Andere Bezeichnung: MEK1

Hintergrund: Background: MEK1 is an activator and kinase for MAP and ERK kinases. It is a serine/threonine kinase essential to the MAP kinase signal transduction pathway which is involved in a multitude of cellular processes such as proliferation, differentiation, gene activation, and development. MEK1 displays 85 % identity with MEK2. Although MEK1 and MEK2 have been found to be functionally similar, they may serve non-redundant functions. Both are required for cellular proliferation and may play a role in tumorigenesis.

Gen-ID: 5604

NCBI Accession: NP_002746

UniProt: Q02750

Pathways: MAPK Signalweg, RTK Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling