Renin Antikörper

Produktnummer ABIN7269913

Produktdetails anti-Renin Antikörper

Target: Renin (REN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Renin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Renin Rabbit mAb

Kreuzreaktivität: Human

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human Renin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Renin

Target: Renin (REN)

Andere Bezeichnung: REN (REN Produkte)

Synonyme: HNFJ2 antikoerper, RATRENAA antikoerper, RENAA antikoerper, Ren1 antikoerper, D19352 antikoerper, Ren antikoerper, Ren-1 antikoerper, Ren-A antikoerper, Ren1c antikoerper, Ren1d antikoerper, Rn-1 antikoerper, Rnr antikoerper, renin antikoerper, renin 1 structural antikoerper, REN antikoerper, Ren antikoerper, Ren1 antikoerper, ren antikoerper

Hintergrund: Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008],HNFJ2,Blood,Blood_Blood Pressure regulation,Cardiovascular,REN

Molekulargewicht: 47kDa

Gen-ID: 5972

UniProt: P00797

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour