PSMD1 Antikörper (AA 794-953)

Produktnummer ABIN7269586

Produktdetails anti-PSMD1 Antikörper

Target: PSMD1 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 1 (PSMD1))

Bindungsspezifität: AA 794-953

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: PSMD1 Rabbit pAb

Sequenz: DLKMPKVQYK SNCKPSTFAY PAPLEVPKEK EKEKVSTAVL SITAKAKKKE KEKEKKEEEK MEVDEAEKKE EKEKKKEPEP NFQLLDNPAR VMPAQLKVLT MPETCRYQPF KPLSIGGIII LKDTSEDIEE LVEPVAAHGP KIEEEEQEPE PPEPFEYIDD

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 794-953 of human PSMD1 (NP_002798.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PSMD1

Target: PSMD1 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 1 (PSMD1))

Andere Bezeichnung: PSMD1 (PSMD1 Produkte)

Synonyme: P112 antikoerper, Rpn2 antikoerper, S1 antikoerper, 2410026J11Rik antikoerper, zgc:55818 antikoerper, psmd1 antikoerper, proteasome 26S subunit, non-ATPase 1 antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 antikoerper, proteasome 26S subunit, non-ATPase 1 L homeolog antikoerper, PSMD1 antikoerper, Psmd1 antikoerper, psmd1 antikoerper, psmd1.L antikoerper

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. Alternatively spliced transcript variants have been found for this gene.,PSMD1,P112,Rpn2,S1,Cell Biology & Developmental Biology,Ubiquitin,PSMD1

Molekulargewicht: 102kDa/105kDa

Gen-ID: 5707

UniProt: Q99460

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway