Glutathione Peroxidase 1 Antikörper

Produktnummer ABIN7267434

Produktdetails anti-Glutathione Peroxidase 1 Antikörper

Target: Glutathione Peroxidase 1 (GPX1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Glutathione Peroxidase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: GPX1 Rabbit mAb

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human GPX1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Glutathione Peroxidase 1

Target: Glutathione Peroxidase 1 (GPX1)

Andere Bezeichnung: GPX1 (GPX1 Produkte)

Synonyme: Gpx antikoerper, ATGPX1 antikoerper, F13D4.40 antikoerper, F13D4_40 antikoerper, GLUTATHIONE PEROXIDASE 1 antikoerper, glutathione peroxidase 1 antikoerper, gshpx1 antikoerper, AI195024 antikoerper, AL033363 antikoerper, CGPx antikoerper, GPx-1 antikoerper, GSHPx-1 antikoerper, GPX1 antikoerper, gpx1 antikoerper, cb690 antikoerper, zgc:92737 antikoerper, zgc:103683 antikoerper, GPXD antikoerper, GSHPX1 antikoerper, GSHPx antikoerper, wu:fd42f12 antikoerper, wu:fj22d06 antikoerper, zgc:101700 antikoerper, glutathione peroxidase Gpx1 antikoerper, glutathione peroxidase antikoerper, glutathione peroxidase 1 antikoerper, glutathione peroxidase 1a antikoerper, glutathione peroxidase family protein antikoerper, proliferating cell nuclear antigen antikoerper, glutathione peroxidase 1b antikoerper, glutathione peroxidase 1 S homeolog antikoerper, gpx1 antikoerper, GPX1 antikoerper, gpx antikoerper, Gpx antikoerper, Gpx1 antikoerper, gpx1a antikoerper, POPTR_0003s12620g antikoerper, Pcna antikoerper, LBL_RS00590 antikoerper, btuE-1 antikoerper, GPX2 antikoerper, gpx1b antikoerper, gpx1.S antikoerper

Hintergrund: The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. This gene contains an in-frame GCG trinucleotide repeat in the coding region, and three alleles with 4, 5 or 6 repeats have been found in the human population. The allele with 4 GCG repeats has been significantly associated with breast cancer risk in premenopausal women. Alternatively spliced transcript variants and multiple pseudogenes of this gene have been identified.,GPXD, GSHPX1,Apoptosis,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Neurodegenerative Diseases,Neuroscience,Signal Transduction,GPX1

Molekulargewicht: 22kDa

Gen-ID: 2876

UniProt: P07203

Pathways: Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom