Glutathione Peroxidase 1 Antikörper (AA 50-203)

Produktnummer ABIN3021456

Produktdetails anti-Glutathione Peroxidase 1 Antikörper

Target: Glutathione Peroxidase 1 (GPX1)

Bindungsspezifität: AA 50-203

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutathione Peroxidase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: GTTVRDYTQM NELQRRLGPR GLVVLGFPCN QFGHQENAKN EEILNSLKYV RPGGGFEPNF MLFEKCEVNG AGAHPLFAFL REALPAPSDD ATALMTDPKL ITWSPVCRND VAWNFEKFLV GPDGVPLRRY SRRFQTIDIE PDIEALLSQG PSCA

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-203 of human GPX1 (NP_000572.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Glutathione Peroxidase 1

Target: Glutathione Peroxidase 1 (GPX1)

Andere Bezeichnung: GPX1 (GPX1 Produkte)

Synonyme: Gpx antikoerper, ATGPX1 antikoerper, F13D4.40 antikoerper, F13D4_40 antikoerper, GLUTATHIONE PEROXIDASE 1 antikoerper, glutathione peroxidase 1 antikoerper, gshpx1 antikoerper, AI195024 antikoerper, AL033363 antikoerper, CGPx antikoerper, GPx-1 antikoerper, GSHPx-1 antikoerper, GPX1 antikoerper, gpx1 antikoerper, cb690 antikoerper, zgc:92737 antikoerper, zgc:103683 antikoerper, GPXD antikoerper, GSHPX1 antikoerper, GSHPx antikoerper, wu:fd42f12 antikoerper, wu:fj22d06 antikoerper, zgc:101700 antikoerper, glutathione peroxidase Gpx1 antikoerper, glutathione peroxidase antikoerper, glutathione peroxidase 1 antikoerper, glutathione peroxidase 1a antikoerper, glutathione peroxidase family protein antikoerper, proliferating cell nuclear antigen antikoerper, glutathione peroxidase 1b antikoerper, glutathione peroxidase 1 S homeolog antikoerper, gpx1 antikoerper, GPX1 antikoerper, gpx antikoerper, Gpx antikoerper, Gpx1 antikoerper, gpx1a antikoerper, POPTR_0003s12620g antikoerper, Pcna antikoerper, LBL_RS00590 antikoerper, btuE-1 antikoerper, GPX2 antikoerper, gpx1b antikoerper, gpx1.S antikoerper

Hintergrund: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,GPXD,GSHPX1,GPX1,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,Neurodegenerative Diseases,GPX1

Molekulargewicht: 10 kDa/22 kDa

Gen-ID: 2876

UniProt: P07203

Pathways: Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom