COX4 antikoerper, COX4-1 antikoerper, COXIV antikoerper, mg:bb02d03 antikoerper, zgc:110058 antikoerper, GB20012 antikoerper, AL024441 antikoerper, Cox4 antikoerper, Cox4a antikoerper, cox4 antikoerper, cox4i1 antikoerper, coxiv antikoerper, BcDNA:AT07685 antikoerper, CG10396 antikoerper, COX IV antikoerper, CX41 antikoerper, CX42 antikoerper, Dmel\CG10396 antikoerper, IV antikoerper, cytochrome c oxidase subunit 4I1 antikoerper, cytochrome c oxidase subunit IV isoform 1 antikoerper, cytochrome c oxidase subunit 4 isoform 1, mitochondrial antikoerper, cytochrome c oxidase polypeptide IV antikoerper, cytochrome c oxidase subunit IV antikoerper, cytochrome c oxidase subunit 4i1 antikoerper, cytochrome c oxidase subunit IV isoform 1 S homeolog antikoerper, Cytochrome c oxidase subunit 4-like antikoerper, COX4I1 antikoerper, cox4i1 antikoerper, LOC412396 antikoerper, Cox4I1 antikoerper, LOC780848 antikoerper, BMEII0322 antikoerper, RSal33209_1582 antikoerper, SJAG_00976 antikoerper, HMPREF0733_11926 antikoerper, Cox4i1 antikoerper, cox4i1.S antikoerper, COX4L antikoerper
Hintergrund
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],COX IV-1, COX4, COX4-1, COXIV, COXIV-1,Cancer,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Mitochondrial metabolism_Oxidative phosphorylation,Neurodegenerative Diseases,Neuroscience,Signal Transduction,COX4I1