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COX IV Antikörper (N-Term)

COX4I1 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2775574
  • Target Alle COX IV (COX4I1) Antikörper anzeigen
    COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))
    Bindungsspezifität
    • 16
    • 14
    • 12
    • 9
    • 8
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 122
    • 57
    • 48
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen
    Wirt
    • 89
    • 35
    • 2
    • 2
    Kaninchen
    Klonalität
    • 86
    • 42
    Polyklonal
    Konjugat
    • 67
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COX IV Antikörper ist unkonjugiert
    Applikation
    • 115
    • 40
    • 39
    • 29
    • 27
    • 26
    • 23
    • 20
    • 14
    • 10
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    AISTSVCVRA HESVVKSEDF SLPAYMDRRD HPLPEVAHVK HLSASQKALK
    Homologie
    Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 85%, Rabbit: 86%, Rat: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against COX4I1. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human COX4I1
    Top Product
    Discover our top product COX4I1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 169 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hwang, Dornbos, Steidemann, Dunivin, Rizzo, LaPres: "Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome." in: Toxicology and applied pharmacology, (2016) (PubMed).

    Geerling, Boon, van der Zon, van den Berg, van den Hoek, Lombès, Princen, Havekes, Rensen, Guigas: "Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice." in: Diabetes, Vol. 63, Issue 3, pp. 880-91, (2014) (PubMed).

    Snyder, Wang, Patton, Arosio, Levi, Earley, Allen, Connor: "Mitochondrial ferritin in the substantia nigra in restless legs syndrome." in: Journal of neuropathology and experimental neurology, Vol. 68, Issue 11, pp. 1193-9, (2009) (PubMed).

  • Target
    COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))
    Andere Bezeichnung
    COX4I1 (COX4I1 Produkte)
    Synonyme
    COX4 antikoerper, COX4-1 antikoerper, COXIV antikoerper, mg:bb02d03 antikoerper, zgc:110058 antikoerper, GB20012 antikoerper, AL024441 antikoerper, Cox4 antikoerper, Cox4a antikoerper, cox4 antikoerper, cox4i1 antikoerper, coxiv antikoerper, BcDNA:AT07685 antikoerper, CG10396 antikoerper, COX IV antikoerper, CX41 antikoerper, CX42 antikoerper, Dmel\CG10396 antikoerper, IV antikoerper, cytochrome c oxidase subunit 4I1 antikoerper, cytochrome c oxidase subunit IV isoform 1 antikoerper, cytochrome c oxidase subunit 4 isoform 1, mitochondrial antikoerper, cytochrome c oxidase polypeptide IV antikoerper, cytochrome c oxidase subunit IV antikoerper, cytochrome c oxidase subunit 4i1 antikoerper, cytochrome c oxidase subunit IV isoform 1 S homeolog antikoerper, Cytochrome c oxidase subunit 4-like antikoerper, COX4I1 antikoerper, cox4i1 antikoerper, LOC412396 antikoerper, Cox4I1 antikoerper, LOC780848 antikoerper, BMEII0322 antikoerper, RSal33209_1582 antikoerper, SJAG_00976 antikoerper, HMPREF0733_11926 antikoerper, Cox4i1 antikoerper, cox4i1.S antikoerper, COX4L antikoerper
    Hintergrund
    Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. COX4I1 is the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme.Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.
    Alias Symbols: COX4, COXIV, MGC72016, COX4-1
    Protein Interaction Partner: SDCBP, COX1, env, APP, UBC, ICT1, TMBIM4, NELFCD,
    Protein Size: 169
    Molekulargewicht
    19 kDa
    Gen-ID
    1327
    NCBI Accession
    NM_001861, NP_001852
    UniProt
    P13073
    Pathways
    Proton Transport
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