ABCC2 Antikörper

Produktnummer ABIN7265737

Produktdetails anti-ABCC2 Antikörper

Target: ABCC2 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ABCC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: MRP2/ABCC2 Rabbit mAb

Kreuzreaktivität: Human

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human MRP2/ABCC2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ABCC2

Target: ABCC2 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))

Andere Bezeichnung: ABCC2 (ABCC2 Produkte)

Synonyme: ABC30 antikoerper, CMOAT antikoerper, DJS antikoerper, MRP2 antikoerper, cMRP antikoerper, AI173996 antikoerper, Abc30 antikoerper, Cmoat antikoerper, Mrp2 antikoerper, ATP binding cassette subfamily C member 2 antikoerper, ATP-binding cassette, sub-family C (CFTR/MRP), member 2 antikoerper, ABCC2 antikoerper, Abcc2 antikoerper

Hintergrund: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine, therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008],ABC30, CMOAT, DJS, MRP2, cMRP,Cancer,Drug resistance,Drug resistance_MRP-related proteins,Endocrine & Metabolism,Signal Transduction,ABCC2

Molekulargewicht: 174kDa

Gen-ID: 1244

UniProt: Q92887

Pathways: Hormone Transport