ABCC2 Antikörper (AA 180-315)
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- Target Alle ABCC2 Antikörper anzeigen
- ABCC2 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))
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Bindungsspezifität
- AA 180-315
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ABCC2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Sequenz
- IFSAFSENNE SSNNPSSIAS FLSSITYSWY DSIILKGYKR PLTLEDVWEV DEEMKTKTLV SKFETHMKRE LQKARRALQR RQEKSSQQNS GARLPGLNKN QSQSQDALVL EDVEKKKKKS GTKKDVPKSW LMKALF
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 180-315 of human MRP2/ABCC2 (NP_000383.1).
- Isotyp
- IgG
- Top Product
- Discover our top product ABCC2 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ABCC2 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))
- Andere Bezeichnung
- ABCC2 (ABCC2 Produkte)
- Synonyme
- ABC30 antikoerper, CMOAT antikoerper, DJS antikoerper, MRP2 antikoerper, cMRP antikoerper, AI173996 antikoerper, Abc30 antikoerper, Cmoat antikoerper, Mrp2 antikoerper, ATP binding cassette subfamily C member 2 antikoerper, ATP-binding cassette, sub-family C (CFTR/MRP), member 2 antikoerper, ABCC2 antikoerper, Abcc2 antikoerper
- Hintergrund
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine, therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.,ABCC2,ABC30,CMOAT,DJS,MRP2,cMRP,Cancer,Drug resistance,MRP-related proteins,Signal Transduction,Endocrine & Metabolism,ABCC2
- Molekulargewicht
- 174 kDa
- Gen-ID
- 1244
- UniProt
- Q92887
- Pathways
- Hormone Transport
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