ADC Antikörper (AA 1-360)

Produktnummer ABIN7265662

Produktdetails anti-ADC Antikörper

Target: ADC (Arginine Decarboxylase (ADC))

Bindungsspezifität: AA 1-360

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: AZIN2 Rabbit pAb

Sequenz: MAGYLSESDF VMVEEGFSTR DLLKELTLGA SQATTDEVAA FFVADLGAIV RKHFCFLKCL PRVRPFYAVK CNSSPGVLKV LAQLGLGFSC ANKAEMELVQ HIGIPASKII CANPCKQIAQ IKYAAKHGIQ LLSFDNEMEL AKVVKSHPSA KMVLCIATDD SHSLSCLSLK FGVSLKSCRH LLENAKKHHV EVVGVSFHIG SGCPDPQAYA QSIADARLVF EMGTELGHKM HVLDLGGGFP GTEGAKVRFE EIASVINSAL DLYFPEGCGV DIFAELGRYY VTSAFTVAVS IIAKKEVLLD QPGREEENGS TSKTIVYHLD EGVYGIFNSV LFDNICPTPI LQKKPSTEQP LYSSSLWGPA

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human AZIN2 (NP_443724.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ADC

Target: ADC (Arginine Decarboxylase (ADC))

Andere Bezeichnung: AZIN2 (ADC Produkte)

Synonyme: MGC134604 antikoerper, azi2 antikoerper, odc2 antikoerper, odc-p antikoerper, odc1l antikoerper, xodc2 antikoerper, ADC antikoerper, AZI2 antikoerper, ODC-p antikoerper, ODC1L antikoerper, 4933429I20Rik antikoerper, AZIN2 antikoerper, Azi2 antikoerper, B930082O19 antikoerper, Odcp antikoerper, RGD1564776 antikoerper, odc1-b antikoerper, arginine decarboxylase antikoerper, antizyme inhibitor 2 antikoerper, biosynthetic arginine decarboxylase SpeA antikoerper, biosynthetic arginine decarboxylase SpeA (ADC) antikoerper, pyruvoyl-dependent arginine decarboxylase antikoerper, antizyme inhibitor 2 S homeolog antikoerper, AZIN2 antikoerper, azin2 antikoerper, adc antikoerper, speA antikoerper, Mrub_2839 antikoerper, MMAH_RS09440 antikoerper, Arnit_1968 antikoerper, Mesil_3114 antikoerper, Trad_0080 antikoerper, Spirs_3255 antikoerper, LOC100233080 antikoerper, Azin2 antikoerper, azin2.S antikoerper

Hintergrund: The protein encoded by this gene belongs to the antizyme inhibitor family, which plays a role in cell growth and proliferation by maintaining polyamine homeostasis within the cell. Antizyme inhibitors are homologs of ornithine decarboxylase (ODC, the key enzyme in polyamine biosynthesis) that have lost the ability to decarboxylase ornithine, however, retain the ability to bind to antizymes. Antizymes negatively regulate intracellular polyamine levels by binding to ODC and targeting it for degradation, as well as by inhibiting polyamine uptake. Antizyme inhibitors function as positive regulators of polyamine levels by sequestering antizymes and neutralizing their effect. This gene encodes antizyme inhibitor 2, the second member of this gene family. Like antizyme inhibitor 1, antizyme inhibitor 2 interacts with all 3 antizymes and stimulates ODC activity and polyamine uptake. However, unlike antizyme inhibitor 1, which is ubiquitously expressed and localized in the nucleus and cytoplasm, antizyme inhibitor 2 is predominantly expressed in the brain and testis and localized in the endoplasmic reticulum-golgi intermediate compartment. Recent studies indicate that antizyme inhibitor 2 is also expressed in specific cell types in ovaries, adrenal glands and pancreas, and in mast cells. The exact function of this gene is not known, however, available data suggest its role in cell growth, spermiogenesis, vesicular trafficking and secretion.,AZIN2,ADC,AZI2,AZIB1,ODC-p,ODC1L,ODCp,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,AZIN2

Molekulargewicht: 22kDa/39kDa/40kDa/49kDa/51kDa

Gen-ID: 113451

UniProt: Q96A70