ADC Antikörper (AA 51-150) (Alexa Fluor 488)

Produktnummer ABIN6977493

Produktdetails anti-ADC Antikörper (Alexa Fluor 488)

Target: ADC (Arginine Decarboxylase (ADC))

Bindungsspezifität: AA 51-150

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADC Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ODCp

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ADC

Target: ADC (Arginine Decarboxylase (ADC))

Andere Bezeichnung: ODCp (ADC Produkte)

Synonyme: MGC134604 antikoerper, azi2 antikoerper, odc2 antikoerper, odc-p antikoerper, odc1l antikoerper, xodc2 antikoerper, ADC antikoerper, AZI2 antikoerper, ODC-p antikoerper, ODC1L antikoerper, 4933429I20Rik antikoerper, AZIN2 antikoerper, Azi2 antikoerper, B930082O19 antikoerper, Odcp antikoerper, RGD1564776 antikoerper, odc1-b antikoerper, arginine decarboxylase antikoerper, antizyme inhibitor 2 antikoerper, biosynthetic arginine decarboxylase SpeA antikoerper, biosynthetic arginine decarboxylase SpeA (ADC) antikoerper, pyruvoyl-dependent arginine decarboxylase antikoerper, antizyme inhibitor 2 S homeolog antikoerper, AZIN2 antikoerper, azin2 antikoerper, adc antikoerper, speA antikoerper, Mrub_2839 antikoerper, MMAH_RS09440 antikoerper, Arnit_1968 antikoerper, Mesil_3114 antikoerper, Trad_0080 antikoerper, Spirs_3255 antikoerper, LOC100233080 antikoerper, Azin2 antikoerper, azin2.S antikoerper

Hintergrund:

Synonyms: Antizyme inhibitor 2, AZIN2, Arginine decarboxylase, ADC, ARGDC, Ornithine decarboxylase-like protein, ODC-like protein, ornithine decarboxylase paralog, ODC-p, AZIN2, ADC, KIAA1945, ODCP

Background: Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding (PubMed:17900240). Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production (PubMed:17900240). Participates in the morphological integrity of the trans-Golgi network (TGN) and functions as a regulator of intracellular secretory vesicle trafficking (PubMed:20188728).

Gen-ID: 113451

UniProt: Q96A70