C-JUN Antikörper (pSer79)

Produktnummer ABIN7232967

Der Kaninchen Polyklonal anti-C-JUN Antikörper (ABIN7232967) detektiert spezifisch C-JUN in IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für C-JUN Antikörper (pSer79) (ABIN7232967)

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C-JUN Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-C-JUN Antikörper

Bindungsspezifität: pSer79

Verwendungszweck: Anti-c-Jun (Phospho-Ser79) Rabbit Polyclonal Antibody

Spezifität: This antibody detects endogenous human, mouse, and rat c-Jun only when phosphorylated at serine 79.

Kreuzreaktivität: Human, Maus, Ratte

Immunogen: Peptide sequence that includes phosphorylation site of Serine 79 (G-A-S(p)-L-K) derived from human c-Jun and conjugated to KLH.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry: use at dilution of 1:50- 1:100.
Immunofluorescence: use at dilution of 1:100- 1:200.
These are recommended working dilutions.
End user should determine optimal dilutions for their applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Konzentration: 1.0 mg/mL

Buffer: PBS (without Mg2 and Ca2 ), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: This antibody is stable for at least one (1) year at -20°C.

Details zu C-JUN

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Andere Bezeichnung: c-Jun

Hintergrund: C-Jun in combination with c-Fos, forms the AP-1 early response transcription factor. It was first identified as the Fos-binding protein p39 and only later rediscovered as the product of the c-jun gene. It is activated through double phosphorylation by the JNK pathway but has also a phosphorylation-independent function

Pathways: MAPK Signalweg, RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteine