C-JUN Antikörper (pThr239)

Produktnummer ABIN7212870

Der Kaninchen Polyklonal Anti-C-JUN Antikörper wurde für WB, ELISA, IP und IHC (p) validiert. Er ist geeignet, C-JUN in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für C-JUN Antikörper (pThr239) (ABIN7212870)

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C-JUN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-C-JUN Antikörper

Bindungsspezifität: pThr239

Verwendungszweck: AP-1 (phospho Thr239) Polyclonal Antibody

Spezifität: Phospho-AP-1 (T239) Polyclonal Antibody detects endogenous levels of AP-1 protein only when phosphorylated at T239.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human AP-1 Phospho-Thr239

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IP (2-5 μg/mg lysate), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu C-JUN

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Andere Bezeichnung: AP-1

Hintergrund: Rabbit Anti-AP-1 (phospho Thr239) Polyclonal Antibody,JUN, Transcription factor AP-1, Activator protein 1, AP1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39,JUN is the putative transforming gene of avian sarcoma virus 17. It encodes Jun proto-oncogene, AP-1 transcription factor subunit which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.,Transcription factor AP-1

Gen-ID: 3725

UniProt: P05412

Pathways: MAPK Signalweg, RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteine