TR4 Antikörper (AA 62-356)
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- Target Alle TR4 (NR2C2) Antikörper anzeigen
- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
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Bindungsspezifität
- AA 62-356
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TR4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human NR2C2 (AA: 62-356) expressed in E. coli.
- Klon
- 8F2E8
- Isotyp
- IgG1
- Top Product
- Discover our top product NR2C2 Primärantikörper
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- Applikationshinweise
- WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
- Andere Bezeichnung
- NR2C2 (NR2C2 Produkte)
- Synonyme
- TAK1 antikoerper, TR2R1 antikoerper, TR4 antikoerper, hTAK1 antikoerper, Tr4 antikoerper, gb:dq017625 antikoerper, im:6911408 antikoerper, mKIAA4145 antikoerper, nuclear receptor subfamily 2 group C member 2 antikoerper, nuclear receptor subfamily 2, group C, member 2 antikoerper, NR2C2 antikoerper, Nr2c2 antikoerper, nr2c2 antikoerper
- Hintergrund
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Description: This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Aliases: TR4, TAK1
- Molekulargewicht
- 65.4 kDa
- Gen-ID
- 7182
- Pathways
- T-Zell Rezeptor Signalweg, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades
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