PTPRF Antikörper (AA 1104-1163)

Produktnummer ABIN7193270

Produktdetails anti-PTPRF Antikörper

Target: PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))

Bindungsspezifität: AA 1104-1163

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PTPRF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human PTPRF (AA: extra 1104-1163) expressed in E. coli.

Klon: 6D7C7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu PTPRF

Target: PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))

Andere Bezeichnung: PTPRF (PTPRF Produkte)

Synonyme: LAR antikoerper, AA591035 antikoerper, LARS antikoerper, RPTP-LAR antikoerper, LARFN5C antikoerper, zf-LAR antikoerper, protein tyrosine phosphatase, receptor type F antikoerper, protein tyrosine phosphatase, receptor type, F antikoerper, protein tyrosine phosphatase, receptor type, f, a antikoerper, PTPRF antikoerper, Ptprf antikoerper, ptprfa antikoerper

Hintergrund:

Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Aliases: LAR, BNAH2

Molekulargewicht: 213 kDa

Gen-ID: 5792

Pathways: EGFR Signaling Pathway