DLC1 Antikörper

Produktnummer ABIN7184062

Produktdetails anti-DLC1 Antikörper

Target: DLC1 (Deleted in Liver Cancer 1 (DLC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLC1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human RHG07.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC:1:50-1:100, IF:1:100-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DLC1

Target: DLC1 (Deleted in Liver Cancer 1 (DLC1))

Andere Bezeichnung: DLC1 (DLC1 Produkte)

Synonyme: ARHGAP7 antikoerper, HP antikoerper, STARD12 antikoerper, p122-RhoGAP antikoerper, rhogap7 antikoerper, DLC-1 antikoerper, StARD12 antikoerper, Dlc-1 antikoerper, A730069N07Rik antikoerper, Arhgap7 antikoerper, dlc-1 antikoerper, RhoGAP antikoerper, Dlc1 antikoerper, DLC1 Rho GTPase activating protein antikoerper, DLC1 Rho GTPase activating protein S homeolog antikoerper, rho GTPase-activating protein 7 antikoerper, deleted in liver cancer 1 antikoerper, DLC1 antikoerper, dlc1.S antikoerper, dlc1 antikoerper, LOC100456847 antikoerper, Dlc1 antikoerper, LOC100729904 antikoerper

Hintergrund:

Background: Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.

Yuan B.Z., Cancer Res. 58:2196-2199(1998).
Nagase T., DNA Res. 7:347-355(2000).
Wilson P.J., Hum. Mutat. 15:156-165(2000).

Aliases: ARHGAP 7 antibody, ARHGAP7 antibody, Deleted in liver cancer 1 antibody, Deleted in liver cancer 1 protein antibody, DLC 1 antibody, Dlc-1 antibody, DLC1 antibody, DLC1 Rho GTPase activating protein antibody, FLJ21120 antibody, HP antibody, HP protein antibody, KIAA1723 antibody, p122 RhoGAP antibody, RHG07_HUMAN antibody, Rho GTPase activating protein 7 antibody, Rho GTPase-activating protein 7 antibody, Rho type GTPase activating protein 7 antibody, Rho-type GTPase-activating protein 7 antibody, StAR related lipid transfer (START) domain containing 12 antibody, StAR related lipid transfer protein 12 antibody, StAR-related lipid transfer protein 12 antibody, STARD 12 antibody, StARD12 antibody, START domain containing protein 12 antibody, START domain-containing protein 12 antibody

UniProt: Q96QB1

Pathways: Tube Formation, Positive Regulation of Endopeptidase Activity