LTK Antikörper

Produktnummer ABIN7183757

Produktdetails anti-LTK Antikörper

Target: LTK (Leukocyte Receptor tyrosine Kinase (LTK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LTK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human LTK.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu LTK

Target: LTK (Leukocyte Receptor tyrosine Kinase (LTK))

Andere Bezeichnung: LTK (LTK Produkte)

Synonyme: LTK antikoerper, ALK antikoerper, TYK1 antikoerper, si:dz107o16.1 antikoerper, leukocyte receptor tyrosine kinase antikoerper, leukocyte tyrosine kinase antikoerper, Ltk antikoerper, LTK antikoerper, ltk antikoerper

Hintergrund:

Background: Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport.

Toyoshima H., Proc. Natl. Acad. Sci. U.S.A. 90:5404-5408(1993).
Krolewski J.J., EMBO J. 10:2911-2919(1991).
Maru Y., Oncogene Res. 5:199-204(1990).

Aliases: Leukocyte receptor tyrosine kinase antibody, Leukocyte tyrosine kinase antibody, Leukocyte tyrosine kinase receptor antibody, Ltk antibody, LTK_HUMAN antibody, Protein tyrosine kinase 1 antibody, TYK 1 antibody, TYK1 antibody

UniProt: P29376

Pathways: RTK Signalweg