CYP2C8 Antikörper

Produktnummer ABIN7183419

Produktdetails anti-CYP2C8 Antikörper

Target: CYP2C8 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP2C8 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human Cytochrome P450 2C8.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000, IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CYP2C8

Target: CYP2C8 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))

Andere Bezeichnung: CYP2C8 (CYP2C8 Produkte)

Synonyme: CPC8 antikoerper, CYPIIC8 antikoerper, MP-12/MP-20 antikoerper, CYP2C74 antikoerper, cpc8 antikoerper, cyp2c8 antikoerper, cypiic8 antikoerper, mp-12/mp-20 antikoerper, cytochrome P450 family 2 subfamily C member 8 antikoerper, Cytochrome P450 2C8 antikoerper, cytochrome P450, family 2, subfamily C, polypeptide 8 antikoerper, cytochrome P450 family 2 subfamily C member 8 S homeolog antikoerper, CYP2C8 antikoerper, CTN_0597 antikoerper, cyp2c8.1.S antikoerper, cyp2c8.1 antikoerper

Hintergrund:

Background: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol).

Romkes M., Biochemistry 30:3247-3255(1991).
Ged C., Biochim. Biophys. Acta 1088:433-435(1991).
Zeldin D.C., Arch. Biochem. Biophys. 322:76-86(1995).

Aliases: CP2C8_HUMAN antibody, CPC8 antibody, CYP2C8 antibody, CYPIIC8 antibody, Cytochrome P450 2C8 antibody, Cytochrome P450 family 2 subfamily C polypeptide 8 antibody, Cytochrome P450 form 1 antibody, Cytochrome P450 IIC2 antibody, Cytochrome P450 MP-12 antibody, Cytochrome P450 MP-20 antibody, Cytochrome P450 subfamily IIC (mephenytoin 4 hydroxylase) polypeptide 8 antibody, Flavoprotein linked monooxygenase antibody, Microsomal monooxygenase antibody, MP 12/MP 20 antibody, P450 form 1 antibody, P450 IIC2 antibody, P450 MP 12/MP 20 antibody, S mephenytoin 4 hydroxylase antibody, S-mephenytoin 4-hydroxylase antibody, Xenobiotic monooxygenase antibody

UniProt: P10632