CYP2C8 Produkte
(Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))
Kategorien
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010].
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Ausgewählte CYP2C8 Kategorien
CYP2C8 Antikörper
High quality antibodies with extensive validation data.
CYP2C8 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CYP2C8 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (2)
Kat. Nr.
ABIN514832
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (2)
Kat. Nr.
ABIN947772
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
ELISA, WB, IHC
Validierungen
- (2)
Kat. Nr.
ABIN6258063
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene CYP2C8 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6214689
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CYP2C8 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122581
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350971
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3078039
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CYP2C8 Produkten
: "Peroxisome proliferator-activated receptor alpha, PPARα, directly regulates transcription of cytochrome P450 CYP2C8." in: Frontiers in pharmacology, Vol. 6, pp. 261, (2015) (PubMed).: "Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity." in: The pharmacogenomics journal, Vol. 11, Issue 2, pp. 121-9, (2011) (PubMed).
: "Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC)." in: American journal of physiology. Renal physiology, Vol. 301, Issue 3, pp. F672-81, (2011) (PubMed).
: "Cytochromes P450: a success story." in: Genome biology, Vol. 1, Issue 6, pp. REVIEWS3003, (2001) (PubMed).
Synonyme und alternative Namen zu CYP2C8
cytochrome P450 family 2 subfamily C member 8 (CYP2C8), Cytochrome P450 2C8 (CTN_0597), cytochrome P450, family 2, subfamily C, polypeptide 8 (CYP2C8), cytochrome P450 family 2 subfamily C member 8 S homeolog (cyp2c8.1.S), cytochrome P450 family 2 subfamily C member 8 (cyp2c8.1), CPC8, cpc8, cyp2c8, CYP2C74, CYPIIC8, cypiic8, MP-12/MP-20, mp-12/mp-20Bezeichner auf Proteinebene für CYP2C8
- P450 form 1
- cytochrome P450 2C8
- cytochrome P450 IIC2
- cytochrome P450 MP-12
- cytochrome P450 MP-20
- cytochrome P450 form 1
- cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8
- flavoprotein-linked monooxygenase
- microsomal monooxygenase
- s-mephenytoin 4-hydroxylase
- xenobiotic monooxygenase
- Cytochrome P450 2C8
- cytochrome P450 CYP2C74
- cytochrome P450, family 2, subfamily C, polypeptide 8
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