CYP2D6 Produkte
(Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))
Kategorien
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug\; sparteine and propafenone, both anti-arrythmic drugs\; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population\; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte CYP2D6 Kategorien
CYP2D6 Antikörper
High quality antibodies with extensive validation data.
CYP2D6 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP2D6 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CYP2D6 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7437350
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN5518823
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, ICC, IF
Validierungen
- (3)
Kat. Nr.
ABIN6258047
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene CYP2D6 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966241
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955249
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955248
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CYP2D6 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350974
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3078040
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7407760
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CYP2D6 Produkten
: "Comparison of Paeoniflorin and Albiflorin on Human CYP3A4 and CYP2D6." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 470219, (2015) (PubMed).: "Production of inhibitory polyclonal antibodies against cytochrome P450s." in: Drug metabolism and pharmacokinetics, Vol. 18, Issue 3, pp. 163-72, (2004) (PubMed).
: "Cytochromes P450: a success story." in: Genome biology, Vol. 1, Issue 6, pp. REVIEWS3003, (2001) (PubMed).
Synonyme und alternative Namen zu CYP2D6
cytochrome P450 family 2 subfamily D member 6 (CYP2D6), cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6), cytochrome 2D6 (CYP2D6), cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6-b), cytochrome P450 family 2 subfamily D member 6 S homeolog (cyp2d6.S), cytochrome P450 family 2 subfamily D member 6 (cyp2d6), cytochrome P450 2D6 (CYP2D6), cytochrome P450 2D6-like (LOC100988273), CPD6, CYP2D, cyp2d2, CYP2D6, cyp2d6-a, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2D42, CYP2DL1, CYPIID6, MGC64445, P450-DB1, P450C2D, P450DB1Bezeichner auf Proteinebene für CYP2D6
- cytochrome P450 2D6
- cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2
- cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2
- cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2
- cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2
- cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6
- cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1
- cytochrome P450-DB1
- debrisoquine 4-hydroxylase
- flavoprotein-linked monooxygenase
- microsomal monooxygenase
- xenobiotic monooxygenase
- CYPIID6
- cytochrome P450 CYP2D42
- cytochrome P450, family 2, subfamily D, polypeptide 6
- cytochrome P450 2D6-like
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