PTGS2 Antikörper

Produktnummer ABIN7180881

Produktdetails anti-PTGS2 Antikörper

Target: PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTGS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Human Cox2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PTGS2

Target: PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))

Andere Bezeichnung: PTGS2 (PTGS2 Produkte)

Synonyme: COX-2 antikoerper, COX2 antikoerper, GRIPGHS antikoerper, PGG/HS antikoerper, PGHS-2 antikoerper, PHS-2 antikoerper, hCox-2 antikoerper, Cox-2 antikoerper, Pghs2 antikoerper, TIS10 antikoerper, Cox2 antikoerper, cox-2 antikoerper, CEF147 antikoerper, PGHS2 antikoerper, PHSII antikoerper, cox2 antikoerper, gripghs antikoerper, pgg/hs antikoerper, pghs-2 antikoerper, phs-2 antikoerper, PTGS2 antikoerper, hcox-2 antikoerper, fj02a10 antikoerper, ptgs2 antikoerper, unp1239 antikoerper, wu:fj02a10 antikoerper, zCOX-2 antikoerper, si:dkey-97o5.6 antikoerper, prostaglandin-endoperoxide synthase 2 antikoerper, prostaglandin G/H synthase 2 antikoerper, prostaglandin-endoperoxide synthase 2S homeolog antikoerper, prostaglandin-endoperoxide synthase 2a antikoerper, prostaglandin-endoperoxide synthase 2b antikoerper, PTGS2 antikoerper, Ptgs2 antikoerper, LOC100136456 antikoerper, ptgs2.S antikoerper, ptgs2 antikoerper, ptgs2a antikoerper, ptgs2b antikoerper

Hintergrund:

Background: Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.

Nathalie Bonnefoy, Mol. Cell. Biol., Apr 2001, 21: 2359 - 2372.
Keith P. Choe, J. Exp. Biol., May 2006, 209: 1696 - 1708
D. Shelley Lupold, PNAS, Sep 1999, 96: 11670.
Axel J. Baumgarten, AACR Meeting Abstracts, Mar 2004, 2004: 1078.

Aliases: COX 2 antibody, COX-2 antibody, COX2 antibody, Cyclooxygenase 2 antibody, Cyclooxygenase 2b antibody, Cyclooxygenase antibody, Cyclooxygenase-2 antibody, Cyclooxygenase2 antibody, EC 1.14.99.1 antibody, fj02a10 antibody, Glucocorticoid-regulated inflammatory cyclooxygenase antibody, Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase antibody, GRIPGHS antibody, hCox 2 antibody, Macrophage activation-associated marker protein P71/73 antibody, OTTHUMP00000033524 antibody, PES-2 antibody, PGG/HS antibody, PGH synthase 2 antibody, PGH2_HUMAN antibody, PGHS 2 antibody, PGHS-2 antibody, PGHS2 antibody, PHS 2 antibody, PHS II antibody, PHS2 antibody, Prostaglandin endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) antibody, Prostaglandin endoperoxide synthase 2 antibody, Prostaglandin G/H synthase 2 antibody, Prostaglandin G/H synthase 2 precursor antibody, Prostaglandin G/H synthase and cyclooxygenase antibody, Prostaglandin G/H synthase antibody, Prostaglandin H2 synthase 2 antibody, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) antibody, Prostaglandin-endoperoxide synthase 2 antibody, PTGS2 antibody, ptgs2a antibody, TIS10 antibody, TIS10 protein antibody, unp1239 antibody, wu:fj02a10 antibody

UniProt: P35354

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation