PTGS2 Antikörper (AA 375-604)

Produktnummer ABIN6146415

Produktdetails anti-PTGS2 Antikörper

Target: PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))

Bindungsspezifität: AA 375-604

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTGS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: PLLPDTFQIH DQKYNYQQFI YNNSILLEHG ITQFVESFTR QIAGRVAGGR NVPPAVQKVS QASIDQSRQM KYQSFNEYRK RFMLKPYESF EELTGEKEMS AELEALYGDI DAVELYPALL VEKPRPDAIF GETMVEVGAP FSLKGLMGNV ICSPAYWKPS TFGGEVGFQI INTASIQSLI CNNVKGCPFT SFSVPDPELI KTVTINASSS RSGLDDINPT VLLKERSTEL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 375-604 of human COX2/PTGS2 (NP_000954.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:4000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-PTGS2 Antikörper (ABIN6146415)

Dai, Ciccotosto, Cappai, Tang, Li, Xie, Xiao, Velkov: "Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis." in: Molecular neurobiology, Vol. 55, Issue 1, pp. 421-434, (2018) (PubMed).

Zhang, Li, Li, Liu, Wei, Qian: "Ceramide enhances COX-2 expression and VSMC contractile hyperreactivity via ER stress signal activation." in: Vascular pharmacology, Vol. 96-98, pp. 26-32, (2017) (PubMed).

Zou, Zhou, Hu, Zhang, Tang, Wen, Xiao, Wang: "Rhizoma Smilacis Glabrae inhibits pathogen-induced upper genital tract inflammation in rats through suppression of NF-κB pathway." in: Journal of ethnopharmacology, Vol. 202, pp. 103-113, (2017) (PubMed).

Details zu PTGS2

Target: PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))

Andere Bezeichnung: PTGS2 (PTGS2 Produkte)

Synonyme: COX-2 antikoerper, COX2 antikoerper, GRIPGHS antikoerper, PGG/HS antikoerper, PGHS-2 antikoerper, PHS-2 antikoerper, hCox-2 antikoerper, Cox-2 antikoerper, Pghs2 antikoerper, TIS10 antikoerper, Cox2 antikoerper, cox-2 antikoerper, CEF147 antikoerper, PGHS2 antikoerper, PHSII antikoerper, cox2 antikoerper, gripghs antikoerper, pgg/hs antikoerper, pghs-2 antikoerper, phs-2 antikoerper, PTGS2 antikoerper, hcox-2 antikoerper, fj02a10 antikoerper, ptgs2 antikoerper, unp1239 antikoerper, wu:fj02a10 antikoerper, zCOX-2 antikoerper, si:dkey-97o5.6 antikoerper, prostaglandin-endoperoxide synthase 2 antikoerper, prostaglandin G/H synthase 2 antikoerper, prostaglandin-endoperoxide synthase 2S homeolog antikoerper, prostaglandin-endoperoxide synthase 2a antikoerper, prostaglandin-endoperoxide synthase 2b antikoerper, PTGS2 antikoerper, Ptgs2 antikoerper, LOC100136456 antikoerper, ptgs2.S antikoerper, ptgs2 antikoerper, ptgs2a antikoerper, ptgs2b antikoerper

Hintergrund: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.,PTGS2,COX-2,COX2,GRIPGHS,PGG/HS,PGHS-2,PHS-2,hCox-2,Cox2,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Blood,Lipids,PTGS2

Molekulargewicht: 68 kDa

Gen-ID: 5743

UniProt: P35354

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation