IL-13 Antikörper

Produktnummer ABIN7178669

Produktdetails anti-IL-13 Antikörper

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of Human IL13

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:2000, IHC:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Store at -20 °C or -80 °C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IL-13

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Andere Bezeichnung: IL13 (IL13 Produkte)

Synonyme: IL13 antikoerper, IL-13 antikoerper, P600 antikoerper, Il-13 antikoerper, L13 antikoerper, interleukin 13 antikoerper, IL13 antikoerper, Il13 antikoerper

Hintergrund:

Background: IL-13 is produced by T cells and is important in the TH2 response. IL-13 targets include B cells, eosinophils, fibroblasts, mast cells and macrophages. IL-13 binds specifically to IL-13Rα1 that complexes with IL-4Rα to form the Type II IL-4R. Jak1 and Tyk2 are activated and signal through Stat3 and Stat6. IL-13Rα2 is a different gene product, lacks the intracellular domain, does not complex with IL-4Rα and does not signal. The extracellular domain of IL-13Rα2 is often elevated in diseased states. IL-13 plays key roles in airway hyperresponsiveness (AHR) of allergic asthma and modulates resistance to parasitic organisms.

Aliases: Allergic rhinitis antibody, ALRH antibody, BHR 1 antibody, BHR1 antibody, Bronchial hyperresponsiveness 1 (bronchial asthma) antibody, IL 13 antibody, IL-13 antibody, Il13 antibody, IL13_HUMAN antibody, Interleukin 13 antibody, Interleukin-13 antibody, interleukin13 antibody, MGC116786 antibody, MGC116788 antibody, MGC116789 antibody, NC 30 antibody, NC30 antibody, P 600 antibody, P600 antibody

UniProt: P35225

Pathways: JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport