SLC22A17 Antikörper (AA 1-99) (HRP)

Produktnummer ABIN7170143

Produktdetails anti-SLC22A17 Antikörper (HRP)

Target: SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))

Bindungsspezifität: AA 1-99

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC22A17 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Solute carrier family 22 member 17 protein (1-99AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SLC22A17

Target: SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))

Andere Bezeichnung: SLC22A17 (SLC22A17 Produkte)

Synonyme: 1700094C23Rik antikoerper, 24p3R antikoerper, AU041908 antikoerper, AW555662 antikoerper, BOIT antikoerper, Boct antikoerper, mBOCT antikoerper, BOCT antikoerper, NGALR antikoerper, NGALR2 antikoerper, NGALR3 antikoerper, hBOIT antikoerper, rBOCT antikoerper, solute carrier family 22 member 17 antikoerper, solute carrier family 22 (organic cation transporter), member 17 antikoerper, solute carrier family 22, member 17 antikoerper, SLC22A17 antikoerper, Slc22a17 antikoerper

Hintergrund:

Background: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.

Aliases: 24p3 receptor antibody, 24p3R antibody, BOCT antibody, BOIT antibody, Brain type organic cation transporter antibody, Brain-type organic cation transporter antibody, hBOIT antibody, Lipocalin-2 receptor antibody, Neutrophil gelatinase associated lipocalin receptor antibody, Neutrophil gelatinase-associated lipocalin receptor antibody, NGAL receptor antibody, NgalR antibody, NGALR2 antibody, NGALR3 antibody, OTTHUMP00000082690 antibody, OTTHUMP00000082691 antibody, Potent brain type organic ion transporter antibody, S22AH_HUMAN antibody, Slc22a17 antibody, Solute carrier family 22 member 17 antibody, Solute carrier family 22 organic cation transporter member 17 antibody

UniProt: Q8WUG5

Pathways: Transition Metal Ion Homeostasis