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SLC22A17 Antikörper (C-Term)

SLC22A17 Reaktivität: Human, Ratte WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500738
  • Target Alle SLC22A17 Antikörper anzeigen
    SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))
    Bindungsspezifität
    • 15
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 25
    • 19
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Ratte
    Wirt
    • 24
    • 1
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SLC22A17 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 13
    • 13
    • 9
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects SLC22A17.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, rat
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    Slc22A17 antibody was raised against a 14 amino acid peptide near the carboxy terminus of the human Slc22A17.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western blot: 1 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))
    Andere Bezeichnung
    SLC22A17 (SLC22A17 Produkte)
    Synonyme
    1700094C23Rik antikoerper, 24p3R antikoerper, AU041908 antikoerper, AW555662 antikoerper, BOIT antikoerper, Boct antikoerper, mBOCT antikoerper, BOCT antikoerper, NGALR antikoerper, NGALR2 antikoerper, NGALR3 antikoerper, hBOIT antikoerper, rBOCT antikoerper, solute carrier family 22 member 17 antikoerper, solute carrier family 22 (organic cation transporter), member 17 antikoerper, solute carrier family 22, member 17 antikoerper, SLC22A17 antikoerper, Slc22a17 antikoerper
    Hintergrund
    The Slc22 family of organic anion and cation transporters (OATs, OCTs, OCTNs) are transmembrane proteins expressed predominantly in kidney and liver. Each contain 12 predicted alpha-helical transmembrane domains (TMDs) and one large extracellular loop between TMDs 1 and 2. Transporters of the SLC22 family function in different ways such as uniporters that mediate facilitated diffusion in either direction (OCTs), as anion exchangers (OAT1, OAT3 and URAT1), and as Na(+)/l-carnitine cotransporter (OCTN2). Slc22 family members participate in the absorption and/or excretion of drugs, xenobiotics, and endogenous compounds in intestine, liver, and kidney, and perform homeostatic functions in brain and heart. Mutations in the Slc22 family may cause specific diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may change drug absorption or excretion. Recent studies show the expression of Slc22A17 as receptor for Lipocalin 2 is relatively high in hematopoietic stem cells.Synonyms: BOCT, BOIT, Brain-type organic cation transporter, Solute carrier family 22 member 17
    Gen-ID
    51310
    UniProt
    Q8WUG5
    Pathways
    Transition Metal Ion Homeostasis
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